Core Functions and Mechanisms

1. Promote Skin Repair and Regeneration

Stimulate the Synthesis of Collagen and Elastin: Activate fibroblasts, significantly increase the production of type I and type III collagen and elastin, improve skin laxity and wrinkles, and enhance elasticity.

Research shows that 0.1% GHK-Cu can increase the collagen synthesis of fibroblasts by more than 30%.

Accelerate Wound Healing: Promote angiogenesis (such as inducing the expression of vascular endothelial growth factor VEGF), attract immune cells (such as macrophages) to the injury site, remove necrotic tissue, and accelerate epidermal regeneration.

Preclinical studies have shown that GHK-Cu can shorten the wound healing time in animal models by up to 30%.

Repair Barrier Function: Enhance the expression of skin barrier proteins (such as filaggrin, loricrin), and improve problems of barrier damage like sensitive skin and eczema.

2. Anti - inflammation and Antioxidation

Inhibition of Inflammatory Factors: Down - regulate pro - inflammatory cytokines (such as TNF - α, IL - 6) to relieve inflammatory skin problems like acne and rosacea.

Free Radical Scavenging: As a carrier of copper ions, GHK - Cu has an activity similar to superoxide dismutase (SOD), neutralizes free radicals (such as ROS), and reduces oxidative damage caused by ultraviolet (UV) rays, pollution, etc.

3. Anti-aging and Hair Health

Delay Cellular Aging: Prolong the lifespan of fibroblasts, inhibit telomere shortening, and reduce the expression of senescence-associated β-galactosidase.

Improve Hair Loss: Promote the proliferation of hair follicle stem cells, extend the anagen phase of hair follicles, reduce hair loss and promote hair growth.

A clinical study shows that hair growth products containing GHK-Cu can increase the hair volume of subjects by more than 12%.

4. Other Potential Effects

Joint Repair: Inhibits chondrocyte apoptosis and alleviates symptoms of osteoarthritis (at the animal experiment stage).

Neuroprotection: Promotes neurite growth and may be used in the research of neurodegenerative diseases (such as Alzheimer's disease).

Skincare and Beauty Field

·Anti-aging Products: Serums, creams, eye creams, etc., highlighting the functions of "anti-wrinkle, firming, and fading fine lines", suitable for mature skin or photoaged skin.

·Repair Products: Used for post-aesthetic treatment (such as laser, microneedling, chemical peeling) repair, relieving redness and sensitivity, and accelerating epidermal regeneration.

·Scalp Care: Hair growth serums, shampoos, improving hair loss and promoting hair growth.

Summary

GHK-CU (Copper Peptide) has become a popular ingredient in the fields of skincare and medical aesthetics due to its multiple functions such as promoting repair, anti-aging, and anti-inflammation. Although some mechanisms still need further research, its potential in improving skin aging, promoting wound healing, and hair health is significant.