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ACE-031 1mg

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ACE-031, also known as Myostatin Inhibitory Peptide 7, is a recombinant protein that fuses the Fc region of human immunoglobulin IgG1 with the Activin Receptor Type IIB (ActRIIB). Its CAS number is 1621169 - 52 - 5, the molecular formula is C₁₃₃H₂₂₇N₄₃O₃₃, and the molecular weight is approximately 2956.49.

Product Details

Mechanism of action: 

Myostatin is a protein that negatively regulates muscle growth. ACE-031 can competitively bind to the myostatin protein, block its downstream signaling pathway, thus lifting the inhibition of muscle growth and promoting muscle growth.


Potential applications:

Treatment of muscle atrophy diseases: Since it can promote muscle growth, it has potential value in the treatment of muscle atrophy - related diseases such as amyotrophic lateral sclerosis and Duchenne muscular dystrophy. Related clinical trials have shown that subcutaneous injection of ACE-031 in boys with Duchenne muscular dystrophy has a trend of maintaining the 6 - minute walk test distance, increasing lean body mass and bone density, and reducing fat mass.

Sports medicine field:

It can be used for sports injury recovery, helping athletes repair damaged muscles faster, increase muscle mass, and improve athletic performance. However, there may currently be ethical and regulatory issues, as this may be regarded as an improper "doping" method.

Improving bone and fat metabolism: Statistically significant changes in serum biomarkers indicate that ACE-031 can also have a positive impact on bone and fat metabolism, helping to maintain bone health and a reasonable fat distribution.


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