I. Basic Information

Chemical Name: (E)-N-[(6 - chloro - 3 - pyridyl)methyl]-N - ethyl - N'- methyl - 2 - nitrovinyldiamine

CAS Number: 150824-47-8

Molecular Formula: C₁₁H₁₅ClN₄O₂

Molecular Weight: 282.72.

II. Mechanism of Action

Targets the nicotinic acetylcholine receptor (nAChR) in the insect nervous system, continuously activates nerve signal transduction, leading to overexcitation, paralysis, and eventually death of insects.

Selective Action: Low affinity for mammalian receptors, thus relatively safe for humans and pets (but the dosage needs to be strictly controlled).

III. Main Application Scenarios

Agriculture and Horticulture:

Control Targets: Sucking pests: aphids, leafhoppers, whiteflies, thrips, planthoppers, etc.

Coleopteran pests: some beetles (such as the Colorado potato beetle).

Crops Suitable for: vegetables, fruits, cotton, rice, ornamental plants, etc.

Application Methods:Foliar spraying, soil treatment, or seed treatment, and the concentration needs to be adjusted according to the type of pests (usually the effective dosage is 50 - 200 g/ha).

Pet Deworming (Veterinary Use):

Product Form: Oral tablets (such as Capstar®), used for emergently killing fleas on cats and dogs.

Features: Fast Flea Elimination: Takes effect within 30 minutes after administration, and kills over 90% of adult fleas within 4 hours.

Short - term Effect: The drug effect lasts about 24 hours, and needs to be combined with long - acting deworming drugs (such as topical drops) to maintain the effect.

IV. Dosage Forms and Precautions

Common Dosage Forms: Agricultural use: 70% water-dispersible granules (WG), 5% emulsifiable concentrate (EC).

Veterinary use: 11 mg, 22 mg oral tablets.

Use Contraindications: Agriculture: Avoid using during the active period of bees (such as flowering period) to prevent water pollution (moderate toxicity to fish).

Pets: Contraindicated for puppies/cats weighing < 2 kg, pregnant animals, and animals with impaired liver and kidney function; Do not mix with pyrethroid drugs (may increase the risk of neurotoxicity).