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Paracetamol
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Paracetamol (also known as acetaminophen) is a commonly used antipyretic and analgesic drug in clinical practice. It is characterized by high safety and few adverse reactions, and is especially suitable for special groups such as children and pregnant women.
Product Details
Product Description
CERTIFICATE OF ANALYSIS
| Test Items | Standard | Test Result |
| Characteristics | A white or almost white crystalline powder | Conform |
| Identification | A.Melting Point:168~172.0ºC | 169.5~170.5ºC |
| C.IR:Consistent with the spectrum obtained with Paracetamol CRS. | Conform | |
| Related substances | Impurity J (chloroacetanilide≤0.001%) | 0 |
| Impurity K (4-aminophenol≤0.005%) | 5.10ppm | |
| Impurity F (4-nitrophenol≤0.05%) | 0 | |
| Any other impurity≤0.05% | 0.02% | |
| Total of other impurities≤0.1% | 0.03% | |
| Loss on drying | ≤0.5% | 0.17% |
| Residue on ignition | ≤0.1% | 0.03% |
| Assay | 99.0-101.0%(calculated on dry basis) | 99.5% |
| Conclusion: | The product above complies with the standard of BP2018/USP42. | |
Paracetamol:
Mainly used for amino acid infusion,due to special wettability, also used in cold cream,osmetics. Serine constitute the human body of several kinds of essential amino acid of protein a, for the construction of protein has a very important role.
The antipyretic and analgesic acetaminophen, this product is a metabolite of , regulates central prostaglandin synthase by inhibiting hypothalamic body temperature. Reduce the synthesis and release of prostaglandin PGE1, bradykinin and histamine. PGE1 mainly acts on the nerve center.
Purpose:
1. Paracetamol is the most commonly used non-inflammatory antipyretic analgesic. Its antipyretic effect is similar, its analgesic effect is weak, and it has no anti-inflammatory and anti rheumatic effect.
2. Paracetamol is used as antipyretic, analgesic and anti rheumatic drugs
3. Paracetamol is used in organic synthesis intermediates, photographic chemicals and non anti-inflammatory, antipyretic and analgesic drugs.
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