BULK QUANTITY DISCOUNT RATES
Mebendazole (mebendazole) is a representative drug of benzimidazole broad - spectrum anthelmintics, mainly used to treat various intestinal parasite infections in humans and animals.
Product Details
Product Details
Product Name | Mebendazole |
Apperance | White powder |
CAS | 31431-39-7 |
MF | C16H13N3O3 |
MW | 295.29 |
Mebendazole (CAS: 31431-39-7) is a benzimidazole carbamate derivative renowned for its potent anthelmintic properties. Structurally, it consists of a benzimidazole ring fused with a carbamate group, which is crucial for its activity against a wide spectrum of parasitic worms. Appearing as a white to off-white crystalline powder, it has low solubility in water, a characteristic that impacts its bioavailability but also allows for formulation into oral tablets and suspensions, often with excipients to enhance dissolution. This compound acts by selectively binding to colchicine-sensitive sites on tubulin, a key protein in the cytoskeleton of parasitic worms. By inhibiting tubulin polymerization, mebendazole disrupts microtubule formation, preventing the synthesis of essential cellular components and ultimately halting glucose uptake, which starves the parasites and leads to their demise.
Application&Function
Mebendazole exhibits remarkable therapeutic efficacy in treating various helminthic infections. It is highly effective against common intestinal nematodes such as Ascaris lumbricoides, Trichuris trichiura, hookworms, and Enterobius vermicularis, commonly known as pinworms. By eliminating adult worms and interfering with the development of larvae, it effectively reduces the parasite burden and alleviates associated symptoms like abdominal pain, diarrhea, and malabsorption. Mebendazole is also used to treat infections caused by cestodes and certain tissue-dwelling parasites. Its broad-spectrum activity makes it a cornerstone in mass deworming programs in regions with high prevalence of helminthiasis. While generally well-tolerated, mebendazole may cause mild side effects, including transient gastrointestinal discomfort, headache, or dizziness. In rare cases, more severe reactions might occur, especially with prolonged use or high doses. However, when administered according to guidelines, mebendazole remains a safe and essential drug for controlling and preventing a wide range of parasitic infections.
Reach out to us now
Email: Joyce@alphapha.com
WhatsApp: +852 4703 9927
Stay Up To Date With Alpha
Get the latest news and promotions sent straight to you!