MGF (Mechano Growth Factor) is a subtype of insulin-like growth factor 1 (IGF-1). Its core function is to initiate muscle repair and growth after mechanical stimulation (such as exercise).

1. Basic Information

Full Name: Mechano Growth Factor

Essence: A member of the IGF-1 family, it is a polypeptide synthesized by the body in response to minor damage to muscles caused by external forces (such as weightlifting or running).

Relationship with PEG-MGF: MGF is the natural form, while PEG-MGF is a product modified with polyethylene glycol (PEG). While their core functions are the same, the modification prolongs their duration of action in the body.

2. Core Functions and Mechanisms

MGF's primary function is muscle repair and growth. Its specific mechanisms and functions are as follows:

Targeted Repair of Damaged Muscle: After muscle stimulation, MGF preferentially accumulates at the site of damage, activating dormant myoblasts.

Promotes cell proliferation and differentiation: Activated myoblasts rapidly divide and differentiate into mature muscle fibers, filling damaged areas and increasing muscle fiber number.

Inhibits muscle cell apoptosis: Reduces the death of damaged muscle cells, maximizing the preservation of existing muscle tissue while creating conditions for new muscle growth.